Electrochemical determination of riboflavin (vb2) using 1, 4 –benzaquinone modified carbon paste electrode

Abstract

In this work a simple and sensitive electroanalytical method for the determination of riboflavin content using 1, 4-benzoquinone modified carbon paste electrode is demonstrated. The method is based on decrease in peak current of 1, 4-benzoquinone on addition of riboflavin. Cyclic voltammetric and linear sweep voltammetric techniques were utilized for the study. The 1, 4-benzoquinone modified carbon paste electrode exhibited a well-defined peak with reproducible peak current values for repetitive measurements; and showed a decrease in peak current value with an increase in riboflavin concentration. The result showed two linear range regions between 0.1 µM - 10 µM and 20 µM - 100 µM, with detection limits of 0.087 µM and 11.51 µM, respectively. The proposed method presented higher sensitivity compared to bare carbon paste electrodes. The modified electrode showed good reproducibility, stability and recovery for the analysis of riboflavin. The developed method would used for electroanalysis of riboflavin in pharmaceutical tablet.