Journal of Pharmacognosy and Phytochemistry Vol. 1 No. 4 2012 www.phytojournal.com Page | 15 Isolation Of Crotepoxide From Berries of Croton Macrostachyus and Evaluation of Its Anti-Leishmanial Activity

Habtamu Gelaw; Legesse Adane; Yinebeb Tariku

dc.contributor.author	Habtamu Gelaw
dc.contributor.author	Legesse Adane
dc.contributor.author	Yinebeb Tariku
dc.date.accessioned	2020-12-07T13:59:22Z
dc.date.available	2020-12-07T13:59:22Z
dc.date.issued	2012
dc.identifier.uri	http://10.140.5.162//handle/123456789/1905
dc.description.abstract	The chloroform extract of the berries of Croton macrostachyus was subjected to column chromatography with chloroform: ethyl acetate mixture as eluting solvent that led to isolation of Crotepoxide. Evaluation of antleishmanial activity of crotepoxide against promatigotes and amastigotes form of L. aethiopica showed that the compound is less active as compared to the reference antileishamnial drugs (amphotericin B and miltefosine). Regardless of the observed activity, further in vivo tests are recommended before drawing any conclusion about the potential of the compound as a new antileishamnial drug candidate. Keyword: Mimusops elengi, Ethnobotany, Phytochemistry, Triterpenoids, Saponins	en_US
dc.language.iso	en	en_US
dc.subject	Mimusops elengi	en_US
dc.subject	Ethnobotany	en_US
dc.subject	Phytochemistry	en_US
dc.subject	Triterpenoids	en_US
dc.subject	Saponins	en_US
dc.title	Journal of Pharmacognosy and Phytochemistry Vol. 1 No. 4 2012 www.phytojournal.com Page \| 15 Isolation Of Crotepoxide From Berries of Croton Macrostachyus and Evaluation of Its Anti-Leishmanial Activity	en_US
dc.type	Article	en_US