Magnitude, Associated Factors and Outcome of Preterm Premature Rupture of Membrane at Nekemte Referral Hospital.

Abstract

Background: The pregnancy complications are increased before term because of increased risk of infection,preterm labor &prematurity.Preterm premature rupture ofd membrane(PPROM) is a major complication of pregnancy and an important cause of perinatal morbidity &mortality.Currently,there is no effective way of preventing spontaneous rupture of membranes.However,it is important that women be well informed regarding maternal,fetal& neonatal complications & perinatal outcome. Objective: To determine the magnitude , associated factors and outcome of mothers with Preterm Prelabor Rupture of Membrane at Nekemte Referral Hospital, East Wollega ,Ethiopia. Methods: prospective cross-sectional study design was conducted on mothers who were admitted with a diagnosis of preterm prelabor rupture of membrane at Nekemte referral hospital from May 1 to July 30/2017.Data was collected using self-administered questionnaires. The data was checked, entered, cleaned&analyzed using SPSS version 20.Descriptive statistic was used to assess the frequency of dependent & independent variables. Bivariate and multivariate were employed to examine the association between dependent & each independent variable. Result:The magnitude of preterm premature rupture membrane at Nekempt referral was 3.8% (31/807). ANC follow up was found independent protective predictor for PPROM after controlling other obstetrics characteristics (AOR=8.4, 95%CI 3, 23.3). Twelve (38.7%) mothers with PPROM had unfavorable outcome (seen at least one complication). The commonest maternal complication was chrioamnionitis (41.7%). No maternal death was documented. Eighteen (58%) perinatal had unfavorable outcome and perinatal death rate was 160 per 1000. The cause of perinatal death were fetal infection 1(20%) and neonatal sepsis 4(80%) Conclusions: The magnitude of PPROM and perinatal outcome and death rate were higher compared to other study in Ethiopia. Getting ANC follow-up was found independent protective for PPROM. Strengthening management of PPROM needed to reduce the poor outcome and Women need to be informed about PPROM on maternal and perinatal complications.