Clinicoepidimological pattern of chronic liver disease among adult patients admitted to medical ward and those on follow up at gastro-intestinalclinic, jimma medical center, jimma town, south west of Ethiopia

Abstract

:Liver disease causes serious public health problems because of its high prevalence worldwide and poor long-term clinical outcome, including premature deaths from liver decompensation and its complications. The major causes of liver diseases are alcohol, infections, autoimmune, genetic, and metabolicand malignancy. Viral hepatitis is the predominant cause for liver disease in low and middle-income countries, while nonalcoholicfatty-liver-disease and alcohol consumption are most frequent etiologies in high-income countries. Viral hepatitis B and C are prevalent in Ethiopia but there are only few studies done in relation to chronic liver disease. Objective: To assess the Clinicoepidimologic pattern of chronic liver disease among adult patients admitted to medical ward and those on follow up at GI clinic with clinical diagnosis chronic liver disease,JMC, Jimma, south west of Ethiopia Methods: A retrospective cross-sectional study design wasemployedby reviewing the charts of patients admitted and on follow up at GI clinic with clinical diagnosis of chronic liver diseasefrom April l, 2017 to April 1, 2018 GC. Out of 102 patientswith clinical diagnosis of chronic liver disease,charts of 96 patients with complete data were reviewed. Check-list containing Sociodemographic, clinical presentation and investigation were completed by data collectors.Data was cleaned, coded and entered to SPSS version 20 for analysis. The result was summarized and presented in tables and figure with descriptions. Result: From totalof 96reviewed charts of patients with diagnosisofchronic liverdisease 66 (68.8%) were males. Most of the patients, 76(79.2%) were in the age group of 20 to 49 years of age. The overall prevalence of HBsAg, alcohol consumption and HCV was 31.2%, 19.8% and 7.2% respectively. In about half of cases (45.8%) the cause of chronic liver disease was not found. Almost all (97.9%) CLD patients had one or more complication that classified them as decompensated chronic liver disease. Conclusion and recommendation: Viral hepatitis and alcohol consumption are common causes of chronic liver disease. Therefore, an initiative needs to be in Prevention of viral hepatitis infections and transmission along with control of alcohol consumption need to be strengthened in order to reduce the burden of chronic liver disease in Ethiopia.