Prevalence of MultidrugResistant Mycobacterium tuberculosis and Associated Risk Factors atGimbiGeneral Hospital, West Wollega Zone, Oromia Regional state, Ethiopia

Abstract

Tuberculosis is a communicable disease caused by Mycobacterium tuberculosis. Tuberculosis is a major public health problem in Africa including Ethiopia. Multidrug-resistant tuberculosis has continued to be a challenge for tuberculosis control globally. Ethiopia is one of the countries with Multidrug-resistant tuberculosis burden. The aim of this study was to assess the prevalence of Multidrug-resistant tuberculosis burdenbacteria and its associated risk factor among patients attending Gimbi General Hospital, west Wollega, OromiaRegional state, Ethiopia. A retrospective study design was used to collect recorded data of Tuberculosisand Multidrugresistant tuberculosis patients attending the hospital from 2012-2017. In addition, questionnaire survey was used to determine the awareness of patients towards the Tuberculosisand Multidrugresistant tuberculosis infection from the patients currently on the follow-up. Primarydata was collected fromTuberculosispatients attending Gimbi General Hospital from September 2017 to September 2018by trained personnel. Finding of the study showed that, the overall prevalence of Tuberculosiscases was 2.38%, among which the prevalence of Tuberculosiscases in male and female were 3% and 1.85%,respectively. Theprevalence of Multidrug-resistant tuberculosis over the years from 2012 to 2018was 0.09%.From the analysis, illiterate, nutritional status, previous treatment, poor lifestyle, low income, misuse of drug, working conditions, and family size were among the major associated risk factors (P<0.001) for the prevalence of Tuberculosisinfection and Multidrug-resistant tuberculosis. So implementation of health education and awareness creation by the concerned bodies using different mechanisms and further research is recommended.