Assessment of hepatitis b vaccination status and associated factors Among healthcare workers working at jumc,jimma, ethiopia

Abstract

Background: Hepatitis B virus (HBV) is a hepatotropic partially double-stranded DNA virus that infects Liver cells, hepatocytes, and recognized as the prototype of a family of hepadnaviruses. Because of their occupational exposure, Health care workers (HCWs) are at highest risk of acquiring HBV infection. WHO recommends vaccination for all HCWs.HBV vaccine is a very safe and effective vaccine that has been reducing incidence of HCC, mortality due to fulminant hepatic failure, and mortality due to chronic liver diseases dramatically. Objective: To assess HBV vaccination status and associated factors among HCWs working at JUMC. Methodology: Institution based cross sectional study design was employed to assess HCWs HBV vaccination status and associated factors from October 1 st to 14 th , 2022. Stratified sampling technique with proportional allocation was used to calculate sample size. Data was entered into the Epi-data version 3.1 and analyzed using SPSS version 21. Both bivariate and multivariable logistic regression models was used. Variables which have p-value less than 0.25 in bivariate analysis was considered as candidate for multivariable analysis while variables which have p-value less than 0.05 in multivariable logistic regression model was considered as statistically significant. Result; The study was done on 296 study participants out of 309 candidate participant with a response rate of 95.7%. The full hepatitis B vaccination status was found to be 48% among the HCWs. Training on infection Prevention, Knowledge about HBV infection and vaccination was found to be significantly associated with vaccination status on multivariate logistic regression model. Conclusion; The study result showed that there is low level of full hepatitis B vaccination status among HCWs at the study area