Determination of The Residual Efficacy of Broflanilide (Vector Tm T500) Insecticide for Indoor Residual Spraying On different wall surfaces: An experimental hut study

Abstract

The rotational use of insecticides with different modes of action for indoor residual spraying (IRS) is recommended for improving malaria vector control and managing insecticide resistance Therefore, a more diversified portfolio of IRS insecticides is required. Previous tests of propoxur, bendiocarb & pirimiphos-methyl have indicated that residual activity is significantly influencedby the wall surface. Inparticular, Bendiocarb showed poor residual lifespan on dung & mud walls. The most commonly used surface in areas where IRS is conducted. An essential component of IRS programs is insecticide resistance monitoring. The detection of resistance to most existing insecticides underscores the urgent need for new insecticides with novel chemistries, capable of delivering enhanced and prolonged control over insecticide-resistant vector populations. Broflanilide is a newly discovered insecticide being considered for malaria vector control.Thus objective of this study was to assess the efficacy of VECTRONTMT500by sapling the insecticide formulation on different wall surfaces Throughout the nine-month hut trial, monthly wall cone bioassay mortality on VECTRON T500 treated hut walls remained > 80%. IRS with broflanilide shows potential to significantly improve the control of malaria transmitted by parathyroid-resistant mosquito vectors and could thus be a crucial addition to determine its decay rates in Ethiopia