Abstract:
Background - Tuberculosis has been one of the major causes of morbidity and mortality in
Ethiopia for long. Treatment outcome of tuberculosis is sub optimal nationally. An
understanding of the factors predisposing to poor outcome may allow the development of
adjunctive treatment strategies or closer clinical monitoring in high-risk individual.
Objective – The main objective of the study was to describe the outcomes of tuberculosis
treatment and to identify factors associated with poor treatment outcome.
Methods and Materials - A prospective cohort study was conducted on all tuberculosis patients
between November 2013 and September 2014 E.C. Data was collected using structured
questionnaire. Data was cleaned, edited and entered to SPSS window version 16.0 for analysis.
The strength of correlation between variables was tested by logistic regression analysis. The
values of p< 0.05 were considered statistically significant. The results are depicted with tables
and figures.
Results - A total of 193 tuberculosis patients with pulmonary(61.2%) and extrapulmonary
(38.8%) tuberculosis were involved in the study with a median age of 26+ 12. The rate of
unsuccessful treatment outcome was 11.4 %. HIV co-infection (OR 21.88 p-0.00) and meningeal
involvement (OR 4.77 p-0.05) significantly increase poor treatment outcome.
Conclusion and Recommendation – HIV co-infection and meningeal involvement increases
rate of poor outcome. Such patients demand close follow up and further study is recommended to
find out and solve the factors behind poor outcome in these group.
Budget and Project Time- Project was conducted by the finance from CBE office of Jimma
University between November 2013 and April 2014E.C
