Abstract:
Background: Vaccines are effective and reliable public health interventions against
infectious outbreaks and pandemics. Inadequate information and fear of vaccination side
effects were delaying some people from accepting the COVID-19 vaccines, which was
hindering efforts to stop the spread of the disease. Therefore, understanding vaccination related behavior is critical in expanding the vaccine coverage to flatten the disease.
Objective: - To assess the willingness to accept COVID 19 Vaccine and associated factors
among adult residents in Assosa town Benishangul Gumuz Region State, western Ethiopia.
Methods: - A community based cross sectional study design triangulated with qualitative
study was used in Assosa town from May 01-30 /2022. Data were collected from 629 adult
residents using a multistage sampling technique for quantitative study. The collected data was
entered into Epi-data 3.1 version and analyzed using SPSS version 25.0 software. Descriptive
statistics were used to describe the characteristics of study participants. The bi-variable and
multivariable logistic regression models were fitted to identify the association between
independent and dependent variables, and a P-value below 0.05 were considered statistically
significant. For the qualitative study, four key informants and eight in-depth interview
participants were used purposefully. And the recorded information was transcribed and
translated then coded and thematically analyzed manually.
Result: - In this study the acceptance of COVID-19 vaccine was 58.5%(364) if available in
the health facility, and male participants was [AOR =1.57, 95%CI (1.112, 2.217)], those
married women [AOR =1.51, 95%CI (1.039, 2.199)], having college degrees and
above[AOR= 2.63, 95%CI (1.369, 5.060)], not received vaccine previously [AOR=1.75, 95%
CI(1.235, 2.484)], tested for COVID-19 [AOR=1.85, 95% CI(1.079, 2.877)] ,friend
diagnosed with COVID-19 [AOR=2.05, 95% CI(1.227, 3.443)], having good knowledge about
COVID-19 vaccine [AOR=1.40, 95% CI(1.015,1.955)], and having positive attitude towards
COVID-19 vaccine [AOR=2.15 (1.486, 3.125)] had significant association with acceptance of
the COVID-19 vaccine. In the qualitative interview most of the participants stated that the
vaccine is causing problems for people because there are serious side effects observed after
vaccination, such as pain and swelling at the site of vaccination.
Conclusion and recommendation: - A considerable proportion of the people have concerns
about the COVID-19 vaccine and are unwilling to accept it if it is available in the health
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facility. The acceptance of the COVID-19 vaccine was significantly associated with male,
married women, college degrees and above, previous vaccine history, friend diagnosis,
COVID-19 test, knowledge and attitude towards COVID-19 vaccine. To enhance adult
population acceptance of the COVID-19 vaccine, evidence-based and tailored information on
COVID-19 vaccines should be provided to adult residences to improve knowledge and
attitude towards COVID-19 vaccines acceptance.