Abstract:
Background: Musculoskeletal infection is spectrum of illnesses which includes Osteomyelitis
(infection/inflammation of bones), Septic arthritis (bacterial infection of joints), pyomyositis
(suppurative infection of the muscles) and cellulites (infection/inflammation of the subcutaneous
tissues).Now a days, community associated MRSA isolates are significantly increasing as
causative agent. However, little is known about the etiology and antibiotics susceptibility pattern
of musculoskeletal infection in Ethiopia particularly in Jimma medical center where empirical
therapy practiced.
Objective: The aim of this study was to assess the etiology and anti-microbial susceptibility
pattern of musculoskeletal infection in adult age >=14years old admitted to orthopedics ward,
Jimma University medical center.
Result: In one year prospective study a total of 60 patient with musculoskeletal infection which
includes spectrum of isolated Pyomyositis 41 (68.3%) patients, Septic arthritis 9(15%) and
osteomyelitis 10(16.7%) were admitted to Jimma University Orthopedic ward. Majority of
participants about 23.3% were between ages of 30-40 years. About 70 % (28) patients had gram
positive cocci and 27.5 %( 11) had gram negative. From 42 bacteria isolated the common
bacteria were S.aureus 52.3% (22/42) followed by E.coli14.3%(6/42), Acinetobacter account for
9.5 %( 4/42).The resistant pattern of S.aureus were for Ceftriaxone (87.5%), for Ampicillin
(94.4%), for vancomycin 53.8 %( 7/13) but less resistant to ciprofloxacin 17.6%(3/17) ,
gentamycin 36.4%(4/15) and oxacillin 28.6(4/14).E.coli resistant pattern for ceftriaxone and
ampicillin was 66.7 %( 4/6), for gentamycin and ciprofloxacin 75 %( 3/4) and clindamycin 80
%( 4/5).
Conclusion: The most common identified bacteria were S.aureus and E.coli with higher drugs
resistant to commonly used antibiotic like ceftriaxone (87.5%, 66.7%) and vancomycin resistant
with S.aureus was 53.8%.
