Abstract:
Contagious bovine pleuropneumonia (CBPP) remains a huge threat to cattle production in sub
Saharan African countries in general and hinders livestock development in Ethiopia in
particular. To this end, there is limited information about this disease in East Wollega. A cross
sectional study was conducted from November, 2017 to June, 2018 in order to determine the
seroprevalence and associated risk factors of CBPP in the Gudeya Bila and Boneya Boshe
districts of East Wollega Zone, Oromia regional state. The study was conducted in the areas
on animal with no history vaccination using simple random sampling to select the study units.
A total of 384 blood samples were collected from the jugular vein of each animal and all
samples were tested by competitive ELISA (c -ELISA) at Bedele Regional Veterinary
Laboratory to detect the specific antibodies to Mycoplasma mycoides subspecies mycoides
Small Colony (MmmSC). Information on risk factors influencing the occurrence of CBPP
using questionnaire survey was collected. Data obtained from both serological and
questionnaire survey was analyzed using SPSS software version 20. Multivariable logistic
regression was used to analyze the association of exposure variables with MmmSC antibodies
circulation. The strength of association between the risk factors and MmmSC antibody
prevalence was assessed using Odds Ratio. The results indicated that, the overall
seroprevalence of CBPP at individual animal-level and herd-level was 8.6% (95%CI: 5.8% -
11.4%) and 26.3% (95%CI: 17.5% -35.2%), respectively. The sero-prevalence of CBPP in
Boneya Boshe and Gudeya Bila were 10.8% and 6.6%, respectively. There was a statistically
significant association in the prevalence of MmmSC antibody with the body condition score
(OR=4.6(1.6-13.2; P<0.01), origin of animals (OR= 12.5(3.1-51.0; P< 0.01) and history of
disease (OR=4.9(1.9-12.9; P< 0.01) at individual animal and herd size (OR: 3.6 (1.3-10.3;
P<0.01) at herd level. This study showed that the overall prevalence of CBPP in study area
was high. This warrants the implementation of appropriate preventive and control practice.
