Abstract:
Background
Drug induced movement disorders remain a significant burden especially among patient
populations taking psychotropic medications. They are associated with adverse effects that can
lead to subjective suffering, stigma, poor compliance to medication and poor quality of life.
However, they are unrecognized and overlooked in clinical settings.
Objectives: To assess psychotropic medications induced movement disorders & associated
factors among mentally ill patients attending follow up treatment at Jimma University Medical
Center psychiatry clinic, Jimma, Southwest Ethiopia, 2019.
Methods: Institution based cross-sectional study design was conducted. A total of 420
participants were selected by systematic random sampling techniques. Data was collected by
semi structured interviewer administered questionnaire and document was reviewed to obtain
patient profile. Psychotropic medications induced movement disorders was assessed by using
Extra Symptom Rating Scale after informed consent was obtained from respondents. Data entry
was done by Epi data version 3.1 and analysis was done by SPSS 22.0statistical software. Binary
Logistic regression was used for comparison of the subjects with and without drug-induced
movement disorders and multivariate logistic regression were used to identify independent
factors. The p-value of <0.05 will be considered as statistically Significant.
Results: The overall prevalence of psychotropic medication induced movement disorder was
40.7% (CI 95%: 36.1, 45.6):- drug induced Parkinsonism 14.4% (CI 95%: 11.0, 18.3), drug
induced akathisia 12.4% (CI 95%: 9.3, 15.4), drug induced tardive dyskinesia 15.4% (CI 95%:
12.0, 19.3) and tardive dystonia 2.2% (CI 95%: 1.7, 3.7) respectively.
Conclusions and Recommendation: The prevalence of psychotropic medications induced
movement disorder in this study was high. Khat was positively associated with drug induced
akathisia and smoking was negatively associated with tar dive dyskinesia. Sex and age were
positively associated with most of drug induced movement disorders. Routine psycho-education
for the patients and families, designing treatment guideline and providing drugs with minimal
side effects is important to reduce these stigmatizing side effects.
